Rattray, Carole A; DaCosta, Vernon E.; Chatoor, J.; Mullings, Anthony M.; Wynter, Hugh H.
Author Affiliation, Ana.
Obstetrics, Gynaecology and Child Health
Large loop excision of the transformation zone (LLETZ): An alternative treatment for cervical intraepithelial neoplasia.
West Indian Medical Journal
Date of Publication
Assesses the technique of large loop excision of the transformation zone (LLETZ) as an alternative to destructive/ablative methods of treatment of cervical intraepithelial neoplasia (CIN), such as cryotherapy, laser vaporization and cone biopsy of the uterine cervix Forty-five patients underwent LLETZ for either diagnostic or therapeutic reasons. It was well-tolerated, and minor bleeding occurred in 4.4% of patients. The quality of the histological specimen was excellent in all cases, only two showing evidence of charring artefacts. In 11 patients (24.4%), a more serious lesion was detected than that found at punch biopsy of the cervix. This method offers a cheaper and more effective alternative to laser vaporization and combines the benefits of the gold standard cone biopsy of the cervix with that of local ablative techniques.....