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Publication Type
Journal Article
Author, Analytic
Fletcher, Horace M.; Mitchell, Sharmaine Y.; Frederick, Joseph; Simeon, Donald T.; Brown, D.
Author Affiliation, Ana.
Obstetrics, Gynaecology and Child Health
Article Title
Intravaginal misoprostol versus dinoprostone as cervical ripening and labor-inducing agents.
Medium Designator
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Connective Phrase
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Journal Title
Obstetrics and Gynecology
Translated Title
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Reprint Status
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Date of Publication
1994
Volume ID
83
Issue ID
2
Page(s)
244-7
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
To compare dinoprostone (prostaglandin E2) and misoprostol (prostaglandin E1) for ripening the cervix and inducing labour at term, 63 women were randomized to receive 100 micrograms misoprostol or 3mg dinoprostone, both as intravaginal tablets. There was no statistical difference between the groups for pre-induction status. The mean Bishop scores before drug insertion were almost identical. Twelve hours after insertion, the mean change in the Bishop score was significantly higher in those receiving misoprostol (5.0 vs 3.3) (p=0.008). However, there was no significant difference in induction-to-delivery interval, spontaneous labour rates, types of delivery, fetal outcome, or maternal complications. Misoprostol is therefore as effective as dinoprostone for inducing labor at term.....
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Keywords
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