Fletcher, Horace M.
Author Affiliation, Ana.
Obstetrics, Gynaecology and Child Health
Misoprostol (prostaglandin E1) for induction of labour.
Postgraduate Doctor - Caribbean
Date of Publication
The usual method of induction of labour for obstetric problems is by use of oxytocin and artificial rupture of membranes. When the cervix is unripe, the use of prostaglandin reduces cervical dystocia and makes induction easier. The usual prostaglandin is dinoprostone, which is expensive. However, prostaglandin is not without risks as hyperstimulation can occur, resulting in fetal distress or demise, abruptio placentae and ruptured uterus. Misoprostol is a synthetic prostaglandin in use since 1989 for inducing labour . Some studies have shown that it is as effective as dinoprostone. Other studies have shown that it is safe but is best used under controlled conditions with strict adherence to a protocol....