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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Robinson, S.; Young, R.E.; Golden, Michael H.
Author Affiliation, Ana.
Basic Medical Sciences; Faculty of Medical Sciences
Article Title
Electrophysiological assessment of brain function in severe malnutrition. Free radicals in the pathogenesis of kwashiorkor
Medium Designator
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Connective Phrase
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Journal Title
Acta Paediatrica
Translated Title
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Reprint Status
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Date of Publication
1995
Volume ID
84
Issue ID
11
Page(s)
1245-1251
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
Brain function in 10 severely malnourished children and matched controls was assessed using spectral analysis of electroencephalographic responses to photic driving during slow-wave sleep. The percentage power in the classical EEG broad-band domains was derived from temporo-occipital records. The malnourished group (5-23 months old; z-score height-for-age -3.2 +/- 0.3, weight-for-height -2.5 +/- 0.3) were tested on admission and on discharge from hospital. No significant differences were found between admission and discharge. Significant differences were found between malnourished and control groups, in the alpha 1 band in the undriven EEG, and in the alpha/beta 1 power ratio while driving at 8 Hz. These electrophysiological abnormalities, persisting despite somatic rehabilitation, must be associated with the chronic rather than the acute aspects of malnutrition, and can index the deviation of brain function from normality....
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Keywords
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