View
Publication Type
Journal Article
Author, Analytic
Singhal, Atul; Davies, Peter; Sahota, Anshoo; Thomas, Peter W.; Serjeant, Graham R.
Author Affiliation, Ana.
Medical Research Council Laboratories (Sickle Cell)
Article Title
Resting metabolic rate in homozygous sickle cell disease
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
American Journal of Clinical Nutrition
Translated Title
n/a
Reprint Status
n/a
Date of Publication
1993
Volume ID
57
Issue ID
1
Page(s)
32-4
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
n/a
Notes
n/a
Abstract
The resting metabolic rate in 20 patients with homozygous sickle cell (SS) disease was 19 percent higher than in 20 age-and sex-matched control subjects with a normal hemoglobin genotype (AA). The difference was not accounted for by differences in lean body mass. It is postulated that this increased energy expenditure reflects the energy expenditure of erythropoietic hyperplasia and leads to a marginal nutritional state that may contribute to the abnormal growth in SS disease.....
read more
Keywords
n/a