Fox, Peter D.; Minninger, K.; Forshaw, M. L.; Vessey, S. J.; Morris, Joanne S.; Serjeant, Graham R.
Author Affiliation, Ana.
Medical Research Council Laboratories (Sickle Cell)
Laser photocoagulation for proliferative retinopathy in sickle haemoglobin C disease.
Date of Publication
Investigates the effect of sectoral, scatter laser photocoagulation on proliferative sickle retinopathy (PSR) by reviewing florescein angiograms of 88 sickle cell-haemoglobin C patients enrolled in a controlled, randomised trial. Follow-up was for a median period of 2.9 years. Complete infarction of all PSR in an eye occurred in 7 of 74 treated eyes and 2 of 60 control eyes. Treatment resulted in significantly greater regression (decrease in number and size of PSR lesions) in eyes of patients aged 25 years at enrollment.....