Simeon, Donald T.; Grantham McGregor, Sally M.; Callender, Joy E. M.; Wong, Michael S.
Author Affiliation, Ana.
Tropical Metabolism Research Unit
Treatment of trichuris trichiura infections improves growth, spelling scores and school attendance in some children
Journal of Nutrition
Date of Publication
Investigates the effects of treating Trichuris trichiura infections in 407 Jamaican children age 6 to 12 years. The children were randomly assigned to receive treatment (albendazole) or a placebo. The outcome variables included growth, tests of reading, spelling and arithmetic, and school attendance. After 6 months of treatment, there was no significant main effect on any of the outcomes. However, there were significant treatment-by-infection intensity interactions with spelling (P 0.05) and body mass index (P 0.01), and a significant treatment-by-stunting interaction with school attendance (P 0.01). In spelling, the children with heavy infections showed improvements with treatment that approached significance.....