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Publication Type
Journal Article
Author, Analytic
Sadler-McKnight, N.,; Jacobs, Helen M.
Author Affiliation, Ana.
Chemistry; Faculty of Pure and Applied Sciences
Article Title
Application of the Folin-Ciocalteau reagent to the determination of salbutamol in pharmaceutical preparations
Medium Designator
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Connective Phrase
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Journal Title
Talanta
Translated Title
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Reprint Status
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Date of Publication
1995
Volume ID
42
Issue ID
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Page(s)
1385-1388
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
A method for the determination of salbutamol in both tablets and syrups is described. It utilizes the reduction of the Folin-Ciocalteau reagent by the phenolic group, monitoring the absorbance of the resulting comples at 760 nm. Results obtained are linear over the range 0-6 mg ml-1 salbutamol. Coloring material was removed by anion exchange chromatography prior to analysis and there was no interference from sucrose, neutral flavourings or the common preservative sodium benzoate. This method appears suitable as a general assay for salbutamol....
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Keywords
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