Lee, Michael G.,; Bennett, Franklyn I.; Hanchard, Barrie
Author Affiliation, Ana.
Helicobater pylori and peptic ulcer diseases.
Postgraduate Doctor - Caribbean
Date of Publication
The recent recognition of the association between Helicobater pylori and peptic ulcer disease (PUD) has revolutionised the appproach to the management of ulcers. Up to 95% of patients with duodenal ulcers and 70-80% with gastric ulcers have H. pylori infection. Peptic ulcer disease is a chronic recurrent disorder. The eradication of H. pylori in patients with PUD results in a significant decrease in the relapse rate of ulceration and alters the natural history of PUD. Several regimes are available for H. pylori eradication and most include two antibiotics given for a least seven days. Patients with either a first or recurrent attacks of peptic ulcer should be considered for eradiction therapy. These patients should also receive an adequate course of an anti-secretory medication for promotion of ulcer healing....