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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Hisada, Michie; Maloney, Elizabeth M.; Sawada, Takashi; Miley, Wendell J.; Palmer, Paulette; Hanchard, Barrie; Goedert, James J.; Manns, Angela
Author Affiliation, Ana.
Department of Pathology
Article Title
Virus markers associated with vertical transmission of human T lymphotropic virus type 1 in Jamaica
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
Clinical Infectious Diseases
Translated Title
n/a
Reprint Status
n/a
Date of Publication
2002
Volume ID
34
Issue ID
12
Page(s)
1551-57
Language
eng
Connective Phrase
n/a
Location/URL
n/a
ISSN
1537-6591
Notes
n/a
Abstract
In a prospective study involving 150 mothers and their offspring in Jamaica, we examined maternal viral factors associated with the risk of transmission of human T lymphotropic virus type 1 (HTLV-1). Overall, the incidence of HTLV-1 infection among children was 8.3 occurrences per 1000 person-months. A higher maternal provirus level (odds ratio [OR], 1.9 per quartile) and a higher HTLV-1 antibody titer (OR, 2.2 per quartile) were independently associated with transmission to children, whereas the presence of anti-Tax antibody was not. Higher maternal antibody titers also were associated with older age at infection among children who were breast-fed for ....
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