Young, Ronald E.; Robinson, Steven
Author Affiliation, Ana.
Department of Basic Medical Sciences
Electroencephalography in severe malnutrition
Wray, Samuel R.; Hernandez, N.; Parshad, Omkar;
Brain, function,behaviour, drugs and disease : Neurosciences in the Caribbean
Place of Publication
Medical and Scientific Development Trust and Caribbean Brain Research Organization
Date of Publication
Series Editor Role
Series Volume Identification
Series Issue Identification
Early malnutrition can cause chronic disturbances in brain structure and function. Rehabilitative measures must be applied vigorously at an early stage and must specifically target recovery of brain function, which must therefore be measurable by simple, reliable and objective methods. Computerised electroencephalographic (cEEG) measures can provide an informative, cost effective adjunct to standard behavioural tests. Early investigations noted persistent changes in alpha, theta and delta EEG rhythms, and in sleep spindle development but failed to quantify degree of deviation from normality in malnourished children. We have demonstrated that the ration of alpha/beta 1 power during quiet sleep, with photic driving at 8 Hz, discriminates strongly (P<0.002) between ten malnourished and ten matched, normal infants. The measure tends to ameliorate, but remains significantly abnormal after rehabilation. It permits insight into the physical bases of the dysfunctions accompanying severe malnutrition, and could assist in devising treatments aimed at optimising brain recovery.....