Fletcher, Horace M.; Rattray, Carole A.; Hanchard, Barrie; Vaughan, Kenneth D.; West, Wayne M.
Author Affiliation, Ana.
Department of Obstetrics, Gynaecology and Child Health
Disseminated donovanosis (Granuloma inguinale) with osteomyelitis of both wrists
West Indian Medical Journal
Date of Publication
Donovanosis is a sexually transmitted infection which presents with genital ulceration and inguinal lymphadenopathy. Rarely, it presents with extra-genital manifestations. We present a case of disseminated donovanosis with cervical ulceration, massive pelvic lymphadenopathy, osteomyelitis of the wrists and septic arthritis of the knees and right elbow. A 23-year-old gravida two presented with wasting, oedema, ascites, bilateral iliac lymphadenopathy, anaemia and a large ulcer of the cervix uteri. Two months later in the outpatient clinic, she was much improved but still had post-coital bleeding and a hyperaemic cervix, suggestive of persistent infection. The course of antibiotics was therefore repeated. Histopathological examination of a specimen from colposcopic biopsy of the cervix uteri revealed granuloma inguinale. She improved after several courses of antibiotics, blood transfusion, surgical debridement and aspiration of affected joints.....