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Publication Type
Journal Article
Author, Analytic
Lindo, John F.; Lyn-Sue-Chin, A. E.; Palmer, C. J.; Lee, Michael G.; Vogel, Peter A.; Robinson, Ralph D.
Author Affiliation, Ana.
Department of Microbiology
Article Title
Seroepidemiology of Helicobacter pylori infection in a Jamaican community
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
Tropical Medicine and International Health
Translated Title
n/a
Reprint Status
n/a
Date of Publication
1999
Volume ID
4
Issue ID
12
Page(s)
862-66
Language
eng
Connective Phrase
n/a
Location/URL
n/a
ISSN
1360-2276
Notes
n/a
Abstract
We researched epidemiologic associations between environmental and demographic factors and prevalence of Helicobacter pylori infection in a suburban Jamaican community. Using a clustered sampling technique, 22 domestic yards enclosing 60 separate households were randomly selected from a local community. All household members (n = 346) were invited to participate following informed consent; the overall compliance rate was 58.9%. A commercial enzyme immunoassay (HMaCAP) was used to detect IgG antibodies raised against H. pylori. Environmental and demographic information was obtained by questionnaire. The seroprevalence of H. pylori was 69.9% (n = 202). Analysis of the independent variables revealed three major components: Component 1 described, collectively, good personal hygiene and sanitation, indoor water supply and absence of straying animals in the peridomestic area; Component 2 included older age, good personal hygiene and large yard size; Component 3 the presence of domestic animals (cats and dogs) and, again, large yard size. These three complexes explained 42.2% of the variability in the data set. Logistic regression showed that Components 2 and 3 were independently associated with H. pylori seropositivity, indicating that a combination of demographic, environmental and zoonotic factors is involved in the spread of H. pylori infections at the tropical community level.....
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