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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Barton, Everard N.; King, S. D.; Douglas, Lawson L.
Author Affiliation, Ana.
Department of Medicine
Article Title
The seroprevalence of hepatitis and retrovirus subjects in Jamaican haemodialysis patients
Medium Designator
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Connective Phrase
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Journal Title
West Indian Medical Journal
Translated Title
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Reprint Status
Refereed
Date of Publication
1998
Volume ID
47
Issue ID
3
Page(s)
105-07
Language
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Connective Phrase
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Location/URL
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ISSN
n/a
Notes
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Abstract
63 haemodialysis (HD) patients and 63 age and gender matched controls were investigated for hepatitis B surface antigen (HbsAg) and antibodies to hepatitis B virus (anti-HBV), hepatitis C virus (anti-HCV), hepatitis D virus (anti-HDV), human immunodeficiency virus types 1 and 2 (anti-HIV-1 and 2) and human T-cell lymphotropic virus type-1 (anti-HTLV-1). The notable finding was an increase in hepatitis B markers, 34.9% in HD patients compared to 19.0% in controls (p<0.02). The seroprevalence of anti-HCV (7.9%, p<0.03) and anti-HTLV-1 (9.5%; p<0.006) was also increased in the patients. Four of the five patients positive for anti-HCV were also seropositive for HBV. Anti-HIV and anti-HDV were not detectable in the HD patients in this study. The possibility of HTLV-1 being transmitted by organ transplantation is raised. The seropositivity rate for hepatitis B and C increased with duration on dialysis, but it is unlikely that it was related to the number of blood transfusions since 50% with no transfusion were HBV seropositive.....
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