Barton, Everard N.; King, S. D.; Douglas, Lawson L.
Author Affiliation, Ana.
Department of Medicine
The seroprevalence of hepatitis and retrovirus subjects in Jamaican haemodialysis patients
West Indian Medical Journal
Date of Publication
63 haemodialysis (HD) patients and 63 age and gender matched controls were investigated for hepatitis B surface antigen (HbsAg) and antibodies to hepatitis B virus (anti-HBV), hepatitis C virus (anti-HCV), hepatitis D virus (anti-HDV), human immunodeficiency virus types 1 and 2 (anti-HIV-1 and 2) and human T-cell lymphotropic virus type-1 (anti-HTLV-1). The notable finding was an increase in hepatitis B markers, 34.9% in HD patients compared to 19.0% in controls (p<0.02). The seroprevalence of anti-HCV (7.9%, p<0.03) and anti-HTLV-1 (9.5%; p<0.006) was also increased in the patients. Four of the five patients positive for anti-HCV were also seropositive for HBV. Anti-HIV and anti-HDV were not detectable in the HD patients in this study. The possibility of HTLV-1 being transmitted by organ transplantation is raised. The seropositivity rate for hepatitis B and C increased with duration on dialysis, but it is unlikely that it was related to the number of blood transfusions since 50% with no transfusion were HBV seropositive.....