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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Palmer, C. J.; Validum, L.; Lindo, John F.; Campa, A.; Validum, C.; Markler, M.; Cuadrado, R.R.; Ager, A.L.
Author Affiliation, Ana.
Department of Microbiology
Article Title
Field evalution of the OptiMAL7 rapid malaria diagnostic test in tracking patient outcomes during anti-malaria therapy in Guyana
Medium Designator
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Connective Phrase
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Journal Title
Transactions of the royal society of tropical medicine and hygiene
Translated Title
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Reprint Status
Refereed
Date of Publication
2000
Volume ID
93
Issue ID
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Page(s)
515-18
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
The OptiMAL rapid test has been proven to be sensitive and specific in both clinical and field trials. This study evaluates the test for diagnosis of Plasmodium falciparum and P vivax infections in Guyana following anti-malarial therapy. Twelve patients identified using microscopy participated in the study and were treated with 600mg quinine every eight hours for five days followed by a single-day treatment on day 6 of Fansidar (1575mg) and primaquine (45mg) The patients were tested using blood films and OptiMAL on day 0, 3 and 5 post-treatment. There was 100% agreement between methods on day 0 and on day 3 there was 45% agreement with 5 patients remaining positive by OptiMAL who were blood film negative. On day 5 there was 83% agreement between the tests. The data showed that OptiMAL was an excellent diagnostic tool for evaluating malaria therapy in endemic areas.....
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