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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Facey, Petrea C.; Pascoe, Keith O. ; Porter, Roy B. ; Jones, A. D.
Author Affiliation, Ana.
Department of Chemistry
Article Title
Investigation of plants used in Jamaican folk medicine for anti- bacterial activity
Medium Designator
n/a
Connective Phrase
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Journal Title
Journal of Pharmacy and Pharmacology
Translated Title
n/a
Reprint Status
Refereed
Date of Publication
1999
Volume ID
51
Issue ID
12
Page(s)
1455-60
Language
n/a
Connective Phrase
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Location/URL
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ISSN
n/a
Notes
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Abstract
We have started a systematic scientific study of folklore medicinal plants currently used as alternative medicine in Jamaican society. In this initial study, extracts of plants widely used by the islanders are studied for antibacterial activity against five common pathogens; Streptococcus group A, Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa and Escherichia coli. These studies revealed that 25% (approx.) of the plant extracts had antimicrobial activity against at least one of the microbes used. Subsequent to these observations, extracts from Mikania micrantha were examined in detail. This led to the isolation of two sesquiterpenoids, mikanolide and dihydromikanolide, with activity against S. aureus and C. albicans. The results suggest that traditional folk medicine could be used as a guide in our continuing search for new natural products with potential medicinal properties.....
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