Jackson, Yvette A.; Lyon, M. A.; Townsend, Norman O.; Bellabe, Kettyna; Soltanik, Fernando
Author Affiliation, Ana.
Department of Chemistry
Reactions of some N-(2,5-dimethoxyaryl)thiobenzamides: En route to an analogue of kuanoniamine A
Journal of the Chemical Society. Perkin transaction 1
Date of Publication
Nitration of 2-aryl-4,7-dimethoxybenzothiazoles 7a-7c produces a mixture of 5-and 6-nitrobenzothiazoles which were distinguished by synthesis of the 2-aryl-4, 7-dimethoxy-6-nitrobenzothiaoles 12a-12c by oxidative cyclization of the corresponding nitrothiobenzanilides. Reaction of N-[2,5-dimethoxy-4-(p-tolysulfonylamino)phenyl]thiobenzamide 17d with base to give 5-methoxy-2-phenyl-6-(p-tolysulfonylamino)benzothiazole 18 with apparent intramolecular replacement of a methoxy group is also described.....