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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Jackson, Yvette A.; Hepburn, Seon A.; Reynolds, William F.
Author Affiliation, Ana.
Department of Chemistry
Article Title
Synthesis of a thiophene analogue of kuanoniamine A
Medium Designator
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Connective Phrase
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Journal Title
Journal of the Chemical Society. Perkin transaction 1
Translated Title
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Reprint Status
Refereed
Date of Publication
2001
Volume ID
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Issue ID
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Page(s)
2237-39
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
Synthesis of 9-methoxycarbonyl-7H-[1] benzothieno[4,5,6-ij][2,7]naphthyridin-7-one (3)– an analogue of kuanoniamine A (1)—via hetero Diels–Alder reaction of crotonaldehyde N,N-dimethylhydrazone with 2-methoxycarbonylbenzo[b]thiophene-4,7-dione and subsequent annelation, is described. The Diels–Alder reaction produced only the adduct with the desired regiochemistry, the structure of which was verified by 2D-NMR experiments.....
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Keywords