View
Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Chen, Avril R.; Reese, Paul B.
Author Affiliation, Ana.
Department of Chemistry
Article Title
Biotransformation of terpenes from Stemodia maritima by Aspergillus niger ATCC 9142
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
Phytochemistry
Translated Title
n/a
Reprint Status
Refereed
Date of Publication
2002
Volume ID
59
Issue ID
1
Page(s)
57-62
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
n/a
Notes
n/a
Abstract
Incubation of temodin (1) in cultures of Aspergillus niger ATCC 9142 resulted in the production of 2a,3b,13-trihydroxy-stemodane (2), 2a,7b,13-trihydroxystemodane (3)and 2a,13,16b-trihydroxystemodane (4), while stemodinone (5) afforded 13,18-dihydroxystemodan-2-one (6) and 13,16b-dihydroxystemodan-2-one (7). Four novel metabolites were obtained from the bioconversion of stemarin (8) by the fungus, namely 18-hydroxystemaran-19-oic acid (9), 7b,18-dihydroxystemaran-19-oic acid (10), 7a,18,19-trihydroxystemarane (11) and 1b-hydroxystemaran-19-oic acid (12). 19-N,N-Dimethylcarbamoxy-13-hydroxystemarane (13) was also transformed to afford 19-N,N-dimethylcarbamoxy-13,17x,18-trihydroxystemarane (14).....
read more