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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Collins, Dwight O.; Reese, Paul B.
Author Affiliation, Ana.
Department of Chemistry
Article Title
Biotransformation of cadina-4,10(15)-dien-3-one and 3a-hydroxycadina-4,10(15)-diene by Curvularia lunata ATCC 12017
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
Phytochemistry
Translated Title
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Reprint Status
Refereed
Date of Publication
2002
Volume ID
59
Issue ID
5
Page(s)
489-92
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
n/a
Notes
n/a
Abstract
Cadina-4,10(15)-dien-3-one (1) was metabolised by Curvularia lunata ATCC 12017 in two different growth media to give three metabolites, one of which, 12-hydroxycadina-4,10(15)-dien-3-one (4), was new. Incubation of 3a-hydroxycadina-4,10(15)-diene (2) with the fungus produced three new analogues, namely, (4S)-1a,3a-dihydroxycadin-10(15)-ene (5), 3a,14-dihydroxycadina-4,10(15)-diene (6) and 3a,12-dihydroxycadina-4,10(15)-diene (7).....
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