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Publication Type
Journal Article
Author, Analytic
McAnuff, Marie; Omoruyi, Felix O.; Morrison, Errol Y. ; Asemota, Helen, N.
Author Affiliation, Ana.
Department of Basic Medical Sciences
Article Title
Plasma and Liver Lipid Distributions in Streptozotocin - induced Diabetic Rats Fed Sapogenin Extract of the Jamaican Bitter Yam ( Dioscorea Polygonoides )
Medium Designator
n/a
Connective Phrase
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Journal Title
Nutrition Research
Translated Title
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Reprint Status
n/a
Date of Publication
2002
Volume ID
22
Issue ID
12
Page(s)
1427-1434
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
Bitter yam (Dioscorea polygonoides) steroidal sapogenin extract and commercial diosgenin were administered to diabetic rats for 21 days. Plasma glucose and lipids were assessed. Liver lipid distributions were also determined. The two dietary supplements fed to diabetic rats resulted in significant decreased body weight gain. The test diets significantly lowered plasma glucose and total cholesterol. Sapogenin extract supplement significantly lowered plasma total triglycerides. Plasma and liver VLDL+LDL-cholesterol were significantly reduced while the HDL fraction was increased in diabetic rats fed the test supplements. These results showed that the consumption of the two supplements may be useful in the management of hypercholesterolemia often associated with diabetes. (AU)....
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