Riley, Cliff K.; Wheatley, Andrew O.; Adebayo, A. S.; Ahmad, I.; ST. A Morrison, E. Y.; Asemota, Helen N.
Author Affiliation, Ana.
Department of Basic Medical Sciences
Implications of amylose content and in virto digestibility of native Jamaican Yam (Dioscorea sp) Starches in the Formulation of Tablets and Capsules for Diabetics
West Indian Medical Journal
Date of Publication
53 Suppl. 1
Tubers such as yams (Dioscorea sp) are widely cultivated in tropical and subtropical regions of the world for their rich carbohydrate and medicinal contents. over 24 different varieties of yams are found in Jamaica belonging to five cultivated species. Starches extracted from Jamaican yams have shown significant variations in physical and and chemical properties among the different varieties and are also of great importance in the formulation of diets and industrial applications. Starch is a multi-purpose escipient in the formulation of tablets and capsules, where it is used as binders, fillers and disintegrants, and it is listed in the top ten excipients. Cornstarch is the most widely used starch in tablet formulation, however previous studies on breadfruit and cocoyam starches have shown promising results. Preliminary data collected on yam starches are encouraging. The degradability of starch when consumed is important especially among diabetics and hyperlipidaemic individuals, as starches that are easily degraded tend to have a higher insulin demand than the slower degrading starches. This can affect the sensitivity to insulin, and influence the developemnt of Type 2 diabetes mellitus, myocardial infarction in women, and reduce HDL cholesteral levels.....