View
Publication Type
Journal Article
Author, Analytic
O'Connor, A.; McFarlane-Anderson, Norma; Duff, Edith M. ; Wright-Pascoe, Rosemarie A.
Author Affiliation, Ana.
Department of Basic Mecical Sciences
Article Title
Oxidative Stress in Adults with Diabetes Mellitus
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
West Indian Medical Journal
Translated Title
n/a
Reprint Status
n/a
Date of Publication
2004
Volume ID
53 Suppl. 1
Issue ID
n/a
Page(s)
44
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
0043-3144 WIMJAD
Notes
n/a
Abstract
Background: Excess oxidative stress has been suggested as a potential mechanism for the increased vascular damasge in diabetes mellitus. Possible sources of oxidative stress in diabetes mellitus include altered carbohydrate and lipid metabolism, decreased levels of antioxidant defenses and most importantly, increased generation of reactive oxygenspecies as a result of the metabolic derangements, lipid peroxidation and glycation. Investigation of oxidative stress as a correltae of glycaemic control is therefore useful in diabetes management. Growing evidence suggests isoprostane as a reliable and sensitive marker of in vivo lipid peroxidation that can easily be measured. (AU)....
read more