O'Connor, N.; Simon, Oswald R.; Gossell-Williams, Maxine D.
Author Affiliation, Ana.
Department of Basic Medical Sciences
Investigation of the Anti-Diabetic Potential of an Extract Prepared from Morinda Citrifolia (Noni) [Abstacts]
West Indian Medical Journal
Date of Publication
Objective: To determine if an aqueous extract prepared from Morinda citrifolia has anti-diabetic properties. Method: Ripened noni fruits were crushed and the juice extracted and freeze-dried. An aqueous extract was prepared from the freeze-dried material and tested on streptozotocin-induced diabetic rats. Sprague-Dawley rats were made diabetic by a single intraperitoneal injection of streptozotocin (60 mg/kg) in citrate buffer pH 4.5. the noni extract was then administered daily to the animals via the oral route with aid of an oral dosing tube in concentrations of 10, 20, and 40mg/kg body weight. The animals' fasting blood glucose levels and weights were then observed once a week for six weeks....