Williams, Winston; Shah, Dipak J.
Author Affiliation, Ana.
Department of Medicine
Renal Histopathological Changes in Adults with Haemoglobin SS Disease. [Abstract]
West Indian Medical Journal
Date of Publication
52 Suppl. 6
Objective: To study patients with haemoglobin SS disease who had percutaneous renal biopsy at the UHWI, Jamaica, for the period 1980-2001. Method: The histological reports were reviewed for glomerular, tubular, interestitial and blood vessel changes. The age, gender, renal function, 24 hour urinary protein excretion and immunological tests recorded were analyzed. Conclusion: The glomerular changes in patients with HbSS disease who develop renal disease are similar to the changes described from other series of patients with HbSS nephropathy. However, an increased number show changes of post-streptococcal glomerulonephritis superimposed on these changes....