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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Arscott, Guyan; Gabay, L.; Craig, H. R.
Author Affiliation, Ana.
Department of Surgery, Radiology, Anaesthesia ans Intensive Care
Article Title
Failure of Bromocriptine Therapy to Control Juvenile Mammary Hypertrophy [Abstract]
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
West Indian Medical Journal
Translated Title
n/a
Reprint Status
n/a
Date of Publication
2003
Volume ID
52
Issue ID
Suppl. .5
Page(s)
16
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
0043-3144
Notes
n/a
Abstract
Introduction: Juvenile mammary hypertrophy is an uncommon syndrome characterized by exaggerated growth at the time of puberty. Attempts to control rapid breast growth using endocrine therapy have generally been met with mixed results. We report a case of juvenile mammary hypertrophy in early adolescence unsuccessfully treated with the anti-prolactin agent bromocriptine. Conclusion: Juvenile mammary hypertrophy occurs in all racial and ethnic groups and has no predisposing factors. Growth is benign and is associated with no other abnormalities. Aetiology is thought to be due to exagerated breast tissue response to normal changes in circulating hormones during puberty. Prolactin is essential for pubertal breast growth; responses to bromocriptine failed to slow the rate of breast enlargement in our patient. The aetiology of her hyperprolactinaemia is uncertain but is unlikely to have contributed to her breast hypertrophy.....
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