Aiken, William D.; Tulloch, T.; Freeman, V. L.; Bennett, Franklyn I.; Coard, Kathleen C.; Panton, B.; Mason, T.; Cudecki, J.; Flanigan, R.
Author Affiliation, Ana.
Department of Surgery, Radiology, Anaesthesia and Intensive Care
Differences in Patient Characteristics in Men of African Descent, with Prostate Cancer from Jamaica and Chicago [Abstract]
West Indian Medical Journal
Date of Publication
Objectives: To make comparisons between prostate cancer in patients of African descent in two diverse environments, one North America, the other Caribbean, in order to determine relative contributions of ethnicity/genetics versus environment. Methods: Incident cases of prostate cancer were identified at each site with baseline demographic and clinical data as well as pre-treated bood samples for measurement of prostate specific antigen (PSA) collected at the time of enrollment. The Gleason scores of patient who had radical prostatectomy were recorded . Demographic comparisons were made by chi-square analysis while mean PSA and Gleason scores were compared by 2-sample tests. Conclusion: Differences in clinical characteristics between men of African descent in environmentally disparate situations probably reflect differences in prostate cancer screening practices as well as awareness and access to healthcare, rather than biological differences influencing clinical presentation and tumor characteristics.....