Schultz, A. A.; Drew, D.; Hewitt, Hermi H.
Author Affiliation, Ana.
UWI School of Nursing
Comparison of Normal Saline and Heparinized for Patency of IV Locks in Neonates
Applied Nursing Research
Date of Publication
In this randomized double-blind experiment of 49 neonatal intensive care unit patients, probable time to catheter failure was significantly longer (p =.0358) for catheters flushed with heparinized saline (median = 127) compared with those flushed with normal saline (median = 39). This is in contrast to the nonsignificant difference (p =.841) in mean scores for six heparin-flushed catheters (M = 41.5 hours, SD = 44.0) compared with 18 saline-flushed catheters (M = 30.4 hours, SD = 20.8) discontinued for reasons other than completion of treatment. We concluded that survival time analysis is necessary when evaluating results of time-dependent studies in which the end point may not be elective.....