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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Mansingh, Akshai; Ware, M.
Author Affiliation, Ana.
Department of Surgery, Radiology, Anaesthesia and Intensive Care
Article Title
Acute Haematogenous Anaerobic Osteomyelitis in Sickle Cell Disease. A Case Report and Review of the Literature
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
West Indian Medical Journal
Translated Title
n/a
Reprint Status
n/a
Date of Publication
2003
Volume ID
52
Issue ID
1
Page(s)
53-55
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
0043-3144
Notes
n/a
Abstract
Patients with sickle cell disease are more susceptible to acute anaerobic osteomyelitis due to focal gut mucosal ischaemia, translocation of bacteria, and seeding in infarcted bone marrow. Modulation of the immune system is also present. The isolation of anaerobic organisms requires a high index of suspicion, correct specimen collection procedures and meticulous specimen handling. Bacteroides is the predominant organism isolated. Intra-osseous gas in the bone may be seen within four days and radiographs are therefore useful earlier than with aerobic osteomyelitis. Surgical debridement and intravenous antibiotics are the mainstay of treatment with the erythrocyte sedimentation rate being relied on heavily to guide conversion to oral antibiotics. Coexistence of septic arthritis is more common with anaerobic osteomyelitis.....
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