Walker, Susan. P.; Thame, Minerva. M.; Chang, Susan M.; Bennett, Franklyn I.; Forrester, Terrence E.
Author Affiliation, Ana.
Department of Obstetrics, Gynaecology and Child Health
The Effects of Growth in utero on cognitive function at age six to eight years [Abstract]
West Indian Medical Journal
Date of Publication
53 Suppl. 2
Objective: To determine whether growth in utero and maternal nutrition status were related to cognitive outcomes in childhood.Design and Methods: Subjects were participants in a prospective cohort study of early life origins of adult disease. Eligible subjects were aged six to eight years at their next scheduled visit to the study clinic and their mothers had abdominal ultrasound measurements at 12, 25 and 35 weeks gestation. One hundred and eighty-six to 269 eligible children attended the clinic and were tested. Three cognutive tests were used - Raven's Progressive Matrices (reasoning ability), Peabody Picture Vocabulary Test (verbal comprehension) and Digit Span Forwards (short -term memory). Mental anthropometry and child anthropometry at birth, during infancy and at testing were measured and maternal and socio-economic characteristics determined by questionnaire. Conclusion: Growth in head circumference in early gestation and maternal nutrition in late gestation may affect later cognitive ability. Further research in this area is needed to confirm these results.....