Wissart, J.; Kulkarni, Santosh K.; Parshad, Omkar
Author Affiliation, Ana.
Department of Obstetrics, Gynaecology and Child Health
Status of Thyroid Gland in Pregnancy and its Relation to Postpartum Depression [Abstract]
West Indian Medical Journal
Date of Publication
53 Suppl. 2
Objective: It is well known that iodine requirement increases during pregnancy. Therefore, mild sub-clinical thyroid dysfunction may occur and produce postpartum depression in mothers. Design and Method: To elucidate this, blood samples were collected from 73 healthy pregnant women attending antenatal clinic, at the University Hospital of the West Indies, at 8, 28, 35 weeks of gestation, and at day one and six weeks postpartum. Total thyroxine (TT4), free triiodothyronine (FT3), thyroid stimulating hormone (TSH), human chronic gonadotropin (HCG), thyroglobulin (TG) and thyroid volume were assessed. The Zung self rating depression scale instrument was administered at 28 weeks of gestation and at 6 weeks postpartum for quantitative measurement of depression. Conclusions: Assessment of Serum TT4 and FT3, TSH and TG levels during pregnancy will enable the clinicians not only to identify those pregnant women who are at risk of developing postpartum depression but also to provide necessary psychiatric or medical treatment. Antenatal screening for thyroid antibodies is also suggested....