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Publication Type
Journal Article
Author, Analytic
Bazuaye, P.E.; Fletcher, Horace M.; Smikle, Monica ; Jackson, Maria D.; McFarlane-Anderson, Norma
Author Affiliation, Ana.
Department of Basic Medical Sciences
Article Title
Class 1 HLA-A-B Haplotypes and Tumour Necrosis Factor (TNF-a) - 308 Polymorphism and Cervical dysplasia [Abstract]
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
West Indian Medical Journal
Translated Title
n/a
Reprint Status
Refereed
Date of Publication
2005
Volume ID
54 Suppl. 2
Issue ID
n/a
Page(s)
72
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
0043-3144
Notes
n/a
Abstract
Objective: To determine whether class 1 HLA-A, -B and TNF-a genetic variants are associated with cervical dysplasia. Methods: Subjects were genotyped for (1) HLA class 1 A & B (CIN III and cancer = 68, controls = 88) and (2) TNF-a (CIN I, II, III, cancer = 240, controls = 102). Conclusions: TNF- SNP-308 inthis population is associated with cervical dysplasia independent of the Class I-A-B MHC genes/haplotypes.....
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