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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Soares, Deanne P.; Reid, Marvin E.; James, Michael V.
Author Affiliation, Ana.
Tropical Medicine Research Institute
Article Title
Age as a predictive factor of mammographic breast density in Jamaican women
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
Clinical Radiology
Translated Title
n/a
Reprint Status
Refereed
Date of Publication
2002
Volume ID
57
Issue ID
6
Page(s)
472-6
Language
English
Connective Phrase
n/a
Location/URL
n/a
ISSN
0009-9260
Notes
n/a
Abstract
Aim: The study determined the relationship between age and other clinical characteristics such as parity, oestrogen use, dietary factors and menstrual history on breast density in Jamaican women. Methods and Materials: A retrospective study was done of 891 patients who attended the breast imaging unit. The clinical characteristics were extracted from the patient records. Mammograms were assessed independently by two radiologists who were blinded to the patient clinical characteristics. Breast densities were assigned using the American College of Radiology (ACR) classification. Results: The concordance between the ACR classification of breast density between the two independent radiologists was 92% with k = 0.76 (SE = 0.02, P < 0.001). Women with low breast density were heavier (81.3 +/- 15.5 kg vs 68.4 +/- 14.3 kg, P < 0.0001, mean +/- standard deviation (SD)) and more obese (body mass index (BMI), 30.3 +/- 5.8 kg m(-2) vs 26.0 +/- 5.2 kg m(-2), P < 0.0001). Mammographic breast density decreased with age. The age adjusted odds ratios (ORs) for predictors significantly related to high breast density were parity, OR = 0.79 (95%CI ratio0.71, 0.88), weight, OR = 0.92 (95% CIratio0.91, 0.95), BMI, OR = 0.83 (95% CIratio0.78, 0.89), menopause, OR = 0.51 (95% CIratio0.36, 0.74) and a history of previous breast surgery, OR 1.6 (95% CIratio1.1, 2.3). Conclusion: The rate decline of breast density with age in the population was influenced by parity and body composition.....
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