Williams, L. A.D; Gossell, M; Sajabi, A; Barton, Everard N.; Fleischhacker, R.
Author Affiliation, Ana.
Basic Medical Sciences (Anatomy, Biochemistry, Physiology)
Angiotensin converting enzyme inhibiting and anti-dipsogenic activities of Euphorbia hirta extracts.
Date of Publication
The methanol extract obtained from the leaves and stems of Euphorbia hirta inhibited the activity of angiotensin converting enzyme (ACE) by 90% and 50% at 500 mg and 160 mg respectively using enzyme linked immunosorbent assay (ELISA). The effect of the extract on thirst was examined using Wistar rats. Intraperitoneal administration of 10mg/100mg body weight of the extract significantly (p<0.05) decreased the amount of water consumed by rats. This effect lasted for 2 hours.....