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Publication Type
Journal Article
Author, Analytic
Williams, L. A.D; Gossell, M; Sajabi, A; Barton, Everard N.; Fleischhacker, R.
Author Affiliation, Ana.
Basic Medical Sciences (Anatomy, Biochemistry, Physiology)
Article Title
Angiotensin converting enzyme inhibiting and anti-dipsogenic activities of Euphorbia hirta extracts.
Medium Designator
n/a
Connective Phrase
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Journal Title
Phytotherapy Research
Translated Title
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Reprint Status
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Date of Publication
1997
Volume ID
11
Issue ID
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Page(s)
401-2
Language
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Connective Phrase
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Location/URL
http:; www3.interscience.wiley.com/cgi-bin/abstract/12675/ABSTRACT
ISSN
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Notes
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Abstract
The methanol extract obtained from the leaves and stems of Euphorbia hirta inhibited the activity of angiotensin converting enzyme (ACE) by 90% and 50% at 500 mg and 160 mg respectively using enzyme linked immunosorbent assay (ELISA). The effect of the extract on thirst was examined using Wistar rats. Intraperitoneal administration of 10mg/100mg body weight of the extract significantly (p<0.05) decreased the amount of water consumed by rats. This effect lasted for 2 hours.....
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