Williams, L.A.D.; Gardner, Michael; Singh, P.D.A.; The, T.L.; Fletcher, Cyril K.; Caleb-Williams, L.S.; Kraus, W.
Author Affiliation, Ana.
Basic Medical Sciences (Anatomy, Biochemistry, Physiology); Faculty of Medical Sciences
Mode of action studies of the acaricidal agent, epingaione
Journal of Invertebrate Reproduction and Development
Date of Publication
Activity directed isolation studies of the ethanol extract of Bontia daphnoides leaves and stems led to the isolation of epingaione, a sesquiterpene furan. The compound showed growth regulatory activities on gravid adult female Boophilus microplus (the southern cattle tick). The compound also caused significant degeneration of funicle cells and reduction in yolk sequestration in the eggs.....