Brown, H. ; Dotto, J. ; Robert, M. ; Salem, R. R.
Author Affiliation, Ana.
Squamous cell carcinoma of the pancreas
Journal of Clinical Gastroenterology
Date of Publication
Department of Surgical Oncology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA.
Squamous cell carcinoma of the pancreas is a rare condition. The incidence has been estimated at approximately 1% of all pancreatic malignancies. The histogenesis is uncertain, but it has been proposed to originate from areas of squamous metaplasia of pancreatic ductal epithelium. We present a case of a 56-year-old man who presented with back pain and was found to have a squamous cell carcinoma of the pancreas without evidence of metastatic disease. Three months after en bloc resection with negative margins and lymph nodes, he presented with widely metastatic disease. A review of the literature on the topic is presented, and the poor prognosis of this rare tumor, despite complete surgical resection, is discussed.....