View
Publication Type
Journal Article
UWI Author(s)
Author, Analytic
King, S. D.; Dodd, R. Y; Haynes, A. Grace; Wynter, Hugh H; Sullivan, M. T; Serjeant, Graham R; Choo Kang, Eric G
Author Affiliation, Ana.
Microbiology
Article Title
Prevalence of antibodies to hepatitis C virus and other markers in Jamaica.
Medium Designator
n/a
Connective Phrase
n/a
Journal Title
West Indian Medical Journal
Translated Title
n/a
Reprint Status
n/a
Date of Publication
1995
Volume ID
44
Issue ID
2
Page(s)
55-7
Language
n/a
Connective Phrase
n/a
Location/URL
n/a
ISSN
n/a
Notes
n/a
Abstract
Three population groups, 1500 blood donors, 513 antenatal women (representing a normal population group) and 250 sicklers (representing a multiply transfused group) were studied to determine the prevalence of hepatitis C viral (HCV) infection in Jamaica. The relationship to liver enzyme levels, hepatitis B infection, syphilis and HIV infection was also investigated. Sera were screened by enzyme-linked immunoassay (EIA) for anti-HCV C100-3 and subsequently tested by a supplementary second generation recombinant immunoblot assay (RIBA). In the blood donors, the prevalence of anti-HCV was low (0.3 - 0.4%), the same level as that reported by several European countries. In the multiply transfused sicklers, the prevalence was more than seven times higher. No HCV infection was detected in the antenatal group. There was little correlation between HCV infection and surrogate markers alanine aminotransferase (ALT) and antibody to hepatitis B core antigen (anti-HBc) and no correlation with sexually transmitted diseases.....
read more
Keywords
n/a