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Publication Type
Journal Article
Author, Analytic
Blank, Michelle; Blank, A.; King, S. D. ; Yashiki, Shinji; Kuwayama, Masahiro; Fujiyama, C.; Gongora, D.; Zaninovic, Vladimir; Cranston, Beverley; Hanchard, Barrie; Imanishi, T.; Manns, Angela; Blattner, William A.; Tajima, Kazuo; Hayami, M.; Fujiyoshi, Toshinobu; Sonoda, Shunro
Author Affiliation, Ana.
Microbiology; Faculty of Medical Sciences
Article Title
Distribution of HLA and haplotypes of Colombian and Jamaican black populations.
Medium Designator
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Connective Phrase
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Journal Title
Tissue Antigens
Translated Title
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Reprint Status
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Date of Publication
1995
Volume ID
45
Issue ID
2
Page(s)
111-116
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
To investigate the genetic background of the black populations of Colombia and Jamaica, the HLA types of 78 Colombian and 98 Jamaican blacks from 2 different socioeconomic groups (Jamaican #1 and Jamaican #2) were determined and the frequencies of HLA genes and haplotypes estimated. A phylogenetic tree based on the HLA gene frequencies revealed that Jamaican #1 and Jamaican #2 were distinct from each other, Jamaican #1 being closely related to Colombian blacks and the Jamaican #2 being closely related to Senegalese and Zairean populations. Three-locus haplotypes of Colombian and Jamaican #1 blacks were an admixture between Africans and Caucasians or South American Indians while Jamaican #2 blacks were relatively homogeneous and appeared to conserve African lineages. The major five-locus HLA haplotypes were not shared among Colombian, Jamaican #1 and Jamaican #2 blacks. These results indicated that the black populations of Colombia and Jamaica were originated from African blacks and admixed variably with Caucasians and South American Indians to make genetic subpopulations in Colombia and Jamaica.....
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Keywords
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