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Publication Type
Journal Article
UWI Author(s)
Author, Analytic
Hanchard, Barrie
Author Affiliation, Ana.
Pathology
Article Title
Clinical manifestations of HTLV-1 infection.
Medium Designator
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Connective Phrase
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Journal Title
Postgraduate Doctor - Caribbean
Translated Title
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Reprint Status
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Date of Publication
1995
Volume ID
11
Issue ID
5
Page(s)
212-216
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
Adult T-cell leukaemia/lymphoma (ATL) and tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM) are the major clinical manifestations of HTLV-1 infection in adults. Susceptibility is related not only to the mode and age of acquisition of the virus but also to genetic, socio-economic and geographic factors. Recently there has been documentation of a number of other disease associations in adults including: polymyositis, uveitis, arthropathy, cystitis and prostatitis. These diseases which exhibit an autoimmune mode of pathogenesis underscore the widespread systemic effects of the virus. In childhood infective dermatitis is a specific marker for HTLV-1 infection with a risk of evolution into either ATL or TSP/HAM in adult life.....
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Keywords
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