Dearden, Claire; Corbin, David O. C.; Prussia, Patsy R.; Williams, Elaine E.; Hanchard, Barrie; Matutes, Estella; Catovsky, Daniel
Author Affiliation, Ana.
Pathology; Faculty of Medical Sciences
Clinical and laboratory features of adult T-cell leukaemia lymphoma in Barbados
Leukemia and Lymphoma
Date of Publication
The clinical and pathological features of 23 Afro-Caribbean patients with adult T-cell leukaemia/lymphoma admitted to the Queen Elizabeth Hospital, Barbados over a 5 year period are described. There were 9 males and 14 females, with a median age of 38 years (range 14-84). Twelve had acute leukaemia, 10 lymphoma (including 4 with solitary extra nodal lesions) and 1 smouldering subtype. Two patients had a past history of tropical spastic paraparesis/HTLV I associated myelopathy (TSP/HAM). The prognosis was poor, with only 3 complete responses to chemotherapy (CHOP) lasting from 9 to 36 months. Concludes that ATLL in Barbados is similar to the disease in other Caribbean islands and Japan, except that in Barbados the age of onset is over a decade younger than in Japan.....