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Publication Type
Journal Article
Author, Analytic
Lowe, Henry I. C.; Watson, Charah T.; Badal, Simone; Toyang, Ngeh J.; Bryant, Joseph
Author Affiliation, Ana.
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Article Title
Cytotoxic effect of Jamaica bissy nut extracts on various cancer cell lines
Medium Designator
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Connective Phrase
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Journal Title
Applied Cell Biology
Translated Title
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Reprint Status
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Date of Publication
2012
Volume ID
1
Issue ID
1
Page(s)
47-49
Language
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Connective Phrase
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Location/URL
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ISSN
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Notes
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Abstract
Given the high incidence of cancer worldwide and one of the main sources of unearthing novel lead molecules being medicinal plants, this research undertook to investigate the possible anti-cancer activity of five bissy plant extracts (hexane, dichloromethane, acetone, methanol and water) against three human cancer cell lines; prostate (PC-3 and DU-145), breast cancer (BC) and mice melanoma (B16). Cytotoxicity was measured using the trypan blue exclusion assay. The hexane extract was the most potent, particularly against, DU-145 and PC-3 cell lines, killing 95% of the cells at 160 g/ml. These results will prove useful for further research and so may serve as leads for the development of new drugs.....
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Keywords
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