Prof. Monica Patricia Smikle

Senior Lecturer in FMS - Microbiology: Faculty of Medical Sciences

Research Interests

• Antimicrobial resistance and molecular studies of enterococci
• Risk factors and aetiology of hospital acquired infection at the UHWI
• The HLA human immunonodeficiency virus associations in Jamaicans
• The HLA and reactive arthritis
• HLA and other molecular investigations on insulin dependent diabetes

Citations

Journal, Article

• Smikle, Monica , Wright-Pascoe, Rosemarie A., Barton, Everard N., Dowe, Gwendolyn, Gilbert, David T., Choo-Kang, Eric G., Morgan, Owen St. C.. Autoantibodies, human T lymphotropic virus type 1 and type 1 diabetes mellitus in Jamaicans
• Akpaka, P.E., Christian, Nicole, Bodonaik, Nabin C., Smikle, Monica . The Prevalence of Coagulase Negative Staphylococci in Blood Cultures at the University Hospital of the West Indies [Abstract]
• Smikle, Monica , Dowe, Gwendolyn, Williams, Evadne M. , Thesiger, Charles H.. Antibodies to hepatitis B virus and hepatitis C virus in residential detoxification clients in Jamaica
• Bazuaye, K.P., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma . Cervical dysplasia in Jamaican women: The role of lifestyle and sexual practices [abstract]
• Barton, Everard N.,, Morgan, Owen St. C., Smikle, Monica , Blattner, William A.. Seroprevalence of HTLV-1 in chronic patients in Jamaica.
• Smikle, Monica ., Christian, Nicole, DeCeulaer, Karel, Barton, Everard N., Roye-Green, Karen J., Dowe, Gwendolyn, McFarlane-Anderson, Norma, Nicholson, G. D.. HLA-DRB Alleles and Systemic Lupus Erythematosus in Jamaicans
• Ragin, Camille, Watt, Angela I., Markovic, Nina, Bunker, Clareann, Edwards, Robert, Eckstein, Stacy, Fletcher, Horace M., Garwood, David, Gollin, Susanne, Jackson, Maria D, Patrick, Alan, Smikle, Monica P., Taioli, Emanuela, Wheeler, Victor, Wilson, Jacque, Younger, Novie O., McFarlane-Anderson, Norma D.. Comparisons of High-risk Cervical HPV infections in Caribbean and US Populations.
• Akpaka, P.E., Smikle, Monica. Molecular epidemiology of methicillin resistant coagulase-negative staphylococci isolates from blood specimens at a tertiary hospital in the Caribbean
• Smikle, Monica , Heslop, Orville D., Vickers, I. E., Dowe, Gwendolyn, Deer, D. , Sue-Ho, Robert, Denbow, Charles E. , Morgan, Owen St. C. , Bain, Brendan C. , Barton, Everard N.. A Serosurvey of Hepatitis B Virus, Hepatitis C Virus, Human T Lymphotropic Virus Type-1 and Syphilis in HIV-1-Infected Patients in Jamaica
• McFarlane-Anderson, N. , Bazuaye, P. E. , Jackson, M. D. , Smikle, M. , Fletcher, H. M. . Cervical dysplasia and cancer and the use of hormonal contraceptives in Jamaican women
• Saunders, Geoffrey, Bodonaik, Nabin C., Smikle, Monica . Diffusible betalactamase from Enterobacter cloacae [Abstract]
• Saunders, Geoffrey, Roye-Green, Karen J., Bodonaik, Nabin C., Smikle, Monica . Plasmid content of Extended Spectrum Betalactamase (ESBL) producing Eschericha coli [Abstract]
• Steel-Duncan, Julianne C., Pierre, Russell B., Evans-Gilbert, Tracy., Rodriquez B., Palmer, Paulette, Whorms, S., Smikle, Monica , Figueroa, J. P., Christie, Celia D.. Outcomes of Infants Born to Women with HIV Infection in Greater Kingston, 2002-2003: A Preliminary Report of the Kingston Paediatric and Perinatal HIV/AIDS (KPAIDS) Programme. [Abstract]
• Jackson, S. T. , Smikle, M. F. , Antoine, M. G. , Roberts, G. D. . Paecilomyces lilacinus fungemia in a Jamaican neonate
• Bazuaye, P. E., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma. The Association Between Tumor Necrosis factor (TNFa) - 308 Polymorphism and Cervical Dysplasia in Jamaican Women [Abstract]
• Bazuaye, P.E., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma. Class 1 HLA-A-B Haplotypes and Tumour Necrosis Factor (TNF-a) - 308 Polymorphism and Cervical dysplasia [Abstract]
• Saunders, Geoffrey , Roye-Green, Karen J., Bodonaik, Nabin C., Smikle, Monica . Plasmid content of extended-spectrum beta-lactamase (ESBL) Escherichia coli [abstract]
• Williams, Winston, Sargeant, Lincoln A., Smikle, Monica , Smith, R., Edwards, H., Shah, Dipak J.. The Outcome of Lupus Nephritis in a Cohort of Black Jamaican Patients. [Abstract]
• Saunders, Geoffrey, Nicholson, Alison M., Roye-Green, Karen J., Akpaka, P. E., Bodonaik, Nabin C., Jackson-Betty, Sandra, Smikle, Monica . Yields from Paired Blood Culture Bottles [Abstract]
• Saunders, Geoffrey, Bodonaik. Nabin C., Smikle, Monica , Jones, A., Jones, J.. Multi-Resistant Escherichia Coli [Abstract]
• Kahwa, E. K. , Sargeant, L. A. , McCaw-Binns, Affette M. , McFarlane-Anderson, N. , Smikle, M. , Forrester, T. , Wilks, Rainford J. . Anticardiolipin antibodies in Jamaican primiparae
• Christian, N. , Smikle, M. F. , DeCeulaer, K. , Daniels, L. , Walravens, M. J. , Barton, E. N. . Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus
• Boyne, Michael S., Smikle, Monica , De La Haye, W.. Hypoglycaemia- was it all in the head
• Akpaka, P.E., Christian, Nicole, Bodonaik, Nabin C., Smikle, Monica . Epidemiology of Blood Isolates of Coagulase Negative Staphlococci at the University Hospital of the West Indies [Abstract]
• Dowe, Gwendolyn, Smikle, Monica , Thesiger, Charles H., Williams, Evadne M. . Bloodborne sexually transmitted infections in patients presenting for substance abuse treatment in Jamaica
• Jackson, S. T. , Smikle, M. F. , Rainford, L. , Wright-Pascoe, R. . Primary cutaneous nocardiosis: an emerging pathogen associated with a peripheral intravenous catheter
• Steel-Duncan, Julianne C., Pierre, Russell B., Evans-Gilbert, Tracy , Rodriguez, B. , Smikle, Monica , Palmer, Paulette, Whorms, S. , Hambleton, Ian R. , Figueroa, J. P. , Christie, Celia D.. Uptake of interventions, outcomes and challenges in caring for HIV-exposed infants in Kingston, Jamaica
• Akpaka, P.E, Tulloch-Reid, A, Justiz-Vaillant, A, Smikle, M.F. Prevalence of human immunodeficiency virus infection in patients with pulmonary tuberculosis at the National Chest Hospital
• Wright-Pascoe, Rosemarie A., Smikle, Monica , Barton, Everard N., James, Owen B. . Limited usefulness of antithyroperoxidase and antithyroglobulin assays in Jamaicans with Graves' disease
• Smikle, Monica , Wright-Pascoe, Rosemarie A., Barton, Everard N. , Morgan, Owen St.C., Christian, Nicole, Dowe, Gwendolyn , Roye-Green, Karen J., Bailey, V. E., James, Owen B.. HLA-DRB3*0101 is associated with Graves' disease in Jamaicans
• Heslop, Orville D., Smikle, Monica P., Vickers, Ivan E., Christian, Nicole A., Harvey, K. M., Figueroa, John P., Brown, Sherline E., Christie, Celia D., Bain, Brendan C., Barton, Everard N.. High Genetic Diversity in Human Immunodeficiency Virus-Type 1 (HIV-1) in Jamaica.
• Christie, Celia D., Bain, Brendan C., Pierre, Russell B., Smikle, Monica , Evans-Gilbert, Tracy , Frederick, Joseph, Mullings, Anthony M., Rattray, Carole A., Pottinger, Audrey M.. HIV/AIDS in women, infants, children and adolescents in Jamaica: A further 'call to action'
• Smikle, Monica , Wharfe, Gillian H., Fletcher, Horace M., Reid, Marvin E., Roye-Green, Karen J., Frederick, Joseph, Pierangeli, Silvia S.. Anticardiolipin, other antiphospholipid antibody tests and diagnosis of the antiphospholipid syndrome
• Wharfe, Gillian H. , Fletcher, Horace M., Smikle, Monica , Frederick, Joseph , Reid, Marvin E.. The prevalence of positive anticardiolipin antibody in Jamaican women with spontaneous abortion and the correlation with past clinical history
• Barton, Everard N.,, Morgan, Owen St. C., Smikle, Monica , Blattner, William A.. Reactive serological test for syphilis in tropical spastic paraparesis: A dilemma.
• Watt, Angela. , Garwood, D. , Jackson, M. , Younger, Novie, Ragin, C. , Smikle, M. , Fletcher, H. , McFarlane-Anderson, N. . High-risk and multiple human papillomavirus (HPV) infections in cancer-free Jamaican women
• Pierre, Russell B., Steel-Duncan, Julianne C., Evans-Gilbert, Tracy, Rodriguez, B., Palmer, Paulette, Smikle, Monica , Whorms, S., Hambleton, Ian R., Figueroa, J. P. , Christie, Celia D.. CDC-Defined Diseases and Opportunistic Infections in Jamaican Children with HIV/AIDS
• Akpaka, P. E. , Christian, N. , Bodonaik, N. C. , Smikle, M. F. . Epidemiology of coagulase-negative Staphylococci isolated from clinical blood specimens at the University Hospital of the West Indies
• Smikle, Monica , Barton, Everard N. , Morgan, Owen St. C. , Luseko, J. , Bailey, V. E., Williams, Evadne M. . The significance of immune disorder in tropical spastic paraparesis
• Steiner, M. J. , Hylton-Kong, T. , Figueroa, J. P. , Hobbs, M. M. , Behets, F. , Smikle, M. , Tweedy, K. , Powell, S. , McNeil, L. , Brathwaite, A. . Does a choice of condoms impact sexually transmitted infection incidence? A randomized, controlled trial
• Saunders, Geoffrey, Bodonaik, Nabin C., Smikle, Monica , Parsad-Asnani, M.. Ceftazidime resistant Salmonella enteritidis in Jamaica
• Bazuaye, P. E., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma. Class 1 HLA-A-B Haplotypes and Tumour Factors (TNF-à) - 308 Polymorphism and Cervical Dysplasia [Abstract]
• Smikle, Monica , Dowe, Gwendolyn, Hylton-Kong, T. , Williams, Elaine E. . Hepatitis B and C viruses and sexually transmitted disease patients in Jamaica
• Vickers, I.E., Alveranga, H., Smikle, M. F.. Clinical and epidemiological characteristics of adult and adolescent patients newly diagnosed with the human immunodeficiency virus at a Jamaica clinic for sexually transmitted infections
• Dowe, Gwendolyn, King, S. D., Smikle, Monica , Wynter, Hugh H., Chout, Roger, Klaskala, W.. Prevalence of viral and bacterial sexually transmitted pathogens in Jamaican pregnant women.
• Smikle, Monica, Morgan, Owen St. C, Barton, Everard N., Bailey, V. E., Blattner, William A.. Serological tests for Lyme disease in patients with tropical spastic paraparesis and healthy Jamaicans.
• Akpaka, P.E., Christian, Nicole, Bodonaik, Nabin C., Smikle, Monica . Molecular Epidemiology of Blood Isolates of Methicillin Resistant Coagulase Negative Staphylococci at the University Hospital of the West Indies. [Abstract]
• Kahwa, Eulalia , Sargeant, Lincoln A., McFarlane-Anderson, Norma , Smikle, Monica , Forrester, Terrence E., Wilks, Rainford J. . Anticardiolipin antibodies and risk of thromboembolic disease in young Jamaican women
• Steiner, M. J., Hylton-Kong, T., Figueroa, J. P., Hobbs, M., Behets, F., Smikle, Monica , Tweedy, K., Powell, S., McNeil, L., Brathwaite, Alfred R.. Does a choice of iondom impact sexually tranmitted infections: A randomized controlled trial [Abstract]
• Barton, Everard N.,, Chung, Edward E., Smikle, Monica , DeCeulaer, Karel, West, Wayne M., Barrow, K. Orrin. Asymptomatic cardiac involvement in systemic lupus erythematosus.
• Simon, S. , Stephenson, S. , Whyte, K. , Stubbs, M. , Vickers, I. E. , Smikle, Monica , Gilbert, David T. , Barton, Everard N.. Prevalence of Chronic Renal Failure in the Diabetic Population at the University Hospital of the West Indies
• Barton, Everard N. , Sargeant, Lincoln A. , Samuels, D. , Smith, R. , James, J. , Wilson, R. , Smith, F. , Falconer, H. , Yeates, Curtis B., Smikle, Monica , Gilbert, David T. . A Survey of Chronic Renal Failure in Jamaica
• Dowe, Gwendolyn , Smikle, Monica , Williams Elaine E. , Hylton-Kong, T. , Shorposner, G. . Non-ulcerative Sexually Transmitted Disease and Human Immunodeficiency Virus Infection in Patients Attending a Sexually Transmitted Disease Clinic in Jamaica
• Dowe, Gwendolyn , Smikle, Monica , King, S. D. , Baum, M. K., Chout, Roger, Williams, Y. . Symptomatic and asymptomatic chlamydial non-gonococcal urethritis in Jamaica: The potential for HIV transmission
• McFarlane-Anderson, Norma, Bazuaye, P.E., Jackson, Maria D., Smikle, Monica, Fletcher, Horace M.. Cervical dysplasia and cancer and the use of hormonal contraceptives in Jamaican women.
• Williams, Winston, Sargeant, L.A., Smikle, Monica, Smith, Roger, Edwards, Heron, Shah, Dipak.. The outcome of lupus nephritis in Jamaican patients
• Vickers, Ivan E, Smikle, Monica. The immunomodulatory effect of antibiotics on the secretion of tumour necrosis factor alpha by peripheral blood mononuclear cells in response to stenotrophomonas maltophilia stimulation
• Bazuaye, K.P., Jackson, Maria D., Smikle, Monica ., Fletcher, Horace M., Rattray, Carole A., McFarlane-Anderson, Norma . Cervical dysplasia and use of hormonal contraceptives in Jamaican women [abstract]
• Gilbert, David T., Morgan, Owen St C., Smikle, Monica , Simeon, Donald T., Barton, Everard N. . HTLV-1 associated polymyositis in Jamaica
• Johnson, N. , Mullings, A. A. , Harvey, K. M. , Alexander, G. , McDonald, D. , Smikle, M. F. , Williams, E. , Palmer, P.M. , Whorms, S. , Figueroa, J. P. , Christie, Celia D. HIV seroprevalence, uptake of interventions to reduce mother-to-child transmission and birth outcomes in greater Kingston, Jamaica
• Dowe, Gwendolyn, Smikle, Monica , King, S. D. , Wynter, Hugh H., Frederick, Joseph, Hylton-Kong, T. . High prevalence of genital Chlamydia trachomatis infection in women presenting in different clinical settings in Jamaica: Implications for control strategies
• Wharfe, Gillian H. , Smikle, Monica , Dowe, Gwendolyn, Buchner, L., Choo-Kang, Eric G., Graham, S., King, D.. Seroprevalence of Hepatitis C Virus in Haemophiliacs in Jamaica.
• Kahwa, Eulalia , Sargeant, Lincoln A., McCaw-Binns, Affette M., McFarlane-Anderson, Norma, Smikle, Monica , Forrester, Terrence E., Wilks, Rainford J.. Anticardiolipin antibodies in Jamaican primiparae [Abstract]
• Smikle, Monica , Dowe, Gwendolyn, Hylton-Kong, T., Williams, Elaine E., Baum, M. K.. Risky behaviour in Jamaican adolescent patients attending a sexually transmitted disease clinic
• Denbow, Charles E. , Barton, Everard N. , Smikle, Monica . The prophylaxis of acute rheumatic fever in a pair of monozygotic twins: The public health implications
• Justiz-Vaillant, A., Smikle, Monica , McFarlane-Anderson, Norma . Novel interactions between streptococcal protein G (SpG) and immunoglobulins [abstract]
• Wilson, Wendell A.,, Morgan, Owen St. C, Barton, Everard N, Smikle, Monica , Hanchard, Barrie, Blattner, William A, Doggett, Sarah, Gharavi, Azzudin E.. IGA antiphospholipid antibodies in HLTV-1-associated tropical spastic paraparesis
• Lee, Michael G.., Arthurs, Milton H., Smikle, Monica , Dowe, Gwendolyn, Levy, V. A., Barton, Everard N.. Antibiotic Sensitivity of Helicobacter Pylori in Jamaica.
• Heslop, O. D. , Smikle, M. F. , Deer, D. , Christian, N. A. , Vickers, I. E. , Harvey, K. M. , Figueroa, J. P. , Christie, C. D. , Bain, B. , Barton, E. N. . Human immunodeficiency virus type-1 (HIV-1) subtypes in Jamaica
• Williams, L.A.D., Igietseme, J.U., Whittaker, J.A., Smikle, Monica, Bailey-Shaw, Y.A., Barton, Everard N. Immunological evidence supporting the use of extracts from boehmeria jamaicensis urb for treating the common cold and sinus infections
• Williams, W. , Sargeant, L. A. , Smikle, M. , Smith, R. , Edwards, H. , Shah, D. . The outcome of lupus nephritis in Jamaican patients
• Smikle, Monica , Barton, Everard N., Morgan, Owen St. C., DeCeulaer, Karel. Photosensitivity and antinuclear antibodies in black patients with systemic lupus erythematosus.
• Smikle, Monica , Barton, Everard N., DeCeulaer, Karel, Williams, Winston, James, Owen B. . Systemic lupus erythematosus, rheumatoid arthritis and HLA phenotypes in Jamaicans.

Abstract

• Brown, Michelle G., Vickers, Ivan E., Salas, R. A., Smikle, Monica P.. Patterns of seroprevalence of dengue virus IgM and IgG antibodies in suspected cases of dengue in Jamaica, 2003-2006.
• Pierre, Russell B., Steel-Duncan, J., Evans-Gilbert, Tracy D., Rodriquez, B., Moore, Jacynth T., Palmer, Paulette M., Smikle, Monica P., Davis, Denver E., Figueroa, John P., Christie, Celia D.. Outcomes of interventions in treating pediatric HIV/AIDS in Jamaican children
• Watt, Angela I., Ragin, C., Younger, Novie O., Garwood, D., Jackson, Maria D., Smikle, Monica P., Fletcher, Horace M., McFarlane-Anderson, Norma D.. Human papilloma-virus (HPV) infection in Jamaican women
• Christian, Nicole, Roye-Green, Karen, Smikle, Monica. Epidemiological study of multidrug resistant Klebsiella pneumoniae by pulsed field gel electrophoresis at the University Hospital of the West Indies 2000-2004. Caribbean Health Research Council 53rd Annual Council and Scientific Meetings, April 2008, Paramaribo, Suriname

Conference Proceedings

• Christie, Celia D.C., Steel-Duncan, J., Palmer, Paulette, Pierre, Russell, Harvey, K.M., Johnson, Nadine, Samuels, L., Dunkley-Thompson, J., Singh-Minott, Indira., Anderson-Allen, Millicent, Billings, Collette, Evans-Gilbert, T., Rodriquez, B., Moore, Jacynth, McDonald-Kerr, C., Taylor, F., Smikle, Monica, Williams, Eric, Whorms, S., Davis, Denver, Mullings, Anthony, Morgan, Orville, McDonald, D., Alexander, G., Onyonyur, A., Hylton-Kong, T., Weller, Peter, Harris, Michelle, Haughton, D., Wo. Effectiveness of highly active antiretroviral drugs in preventing mother to child HIV transmission and reducing HIV-attributable mortality in Jamaican children.
• Pierre, Russell B., Singh-Minott, Indira, Moore, Jacynth T., Carrington, D., Harvey, K., Smikle, Monica P., Figueroa, John .P., Christie, Celia D., Kingston Pediatric & Perinatal HIV/AIDS Program (KPAIDS) Research Group. . Failure of antiretroviral therapy (ART) in Jamaican children: Poster presentation and Abstract