Prof. Horace Melford Fletcher

Research Interests

• Phytooestrogens in Jamaican foods and the impact on hormone dependent disease such as breast cancer, ovarian cancer, endometrial cancer, prostate cancer, cardiovascular disease and osteoporosis
• Cardiovascular disease and osteoporosis after hysterectomy
• Trace elements in placenta
• Mercury in Jamaican fish
• Twins and uterine fibroids

Membership

• Royal College of Obst & Gynae

Citations

Journal, Article

• Johnson, N., Fletcher, Horace M., Reid, Marvin E.. Effect of Pre-Operative Depo-Medroxyprogesterone Acetate Therapy on Uterine Myomata-Associated Menorrhagia in Women Admitted for Surgical Treatment (hysterectomy/myomectomy) [Abstract]
• Scarlett, Marinna D., Isaacs, Melody-Ann, Fredrick-Johnston, Sherifa, Kulkarni, Santosh K., McCaw-Binns, Affette M , Fletcher, Horace M. Maternal mortality in patients admitted to an intensive care unit in Jamaica
• Phillip, H. , Fletcher, Horace M. , Reid, Marvin E.. The Impact of Induced Labour on Postpartum Blood Loss
• Bazuaye, P. E., Fletcher, Horace M., McFarlane-Anderson, Norma. Lifestyle and cervical dysplasia in Jamaica
• Bramwell, G., Levy, Natricha, Wierenga, Andrea M., Fletcher, Horace M.. Factors associated with the development of pre-eclampsia in a Jamaican population [abstract]
• Fletcher, Horace M., Williams, Nadia P., Nicholson, Alison M., Rainford, Lois, Phillip, H., East-Innis, Althea D. Systemic phaeohyphomycosis in pregnancy and the puerperium
• Ewan-Whyte, C., Walker, Susan P., Chang, Susan M., Powell, Christine A., McDonald, D., Fletcher, Horace M.. Factors associated with term low birth at the Victoria Jubliee Hospital [Abstract only]
• Char, Gurendra., Ramjit, Chunilal, Fletcher, Horace M., Harvey, W. . Granulosa Cell Tumour of the Ovary with Bilateral Mature Cystic Teratomas. A Case Report
• Thame, Minerva.M., Osmond, Clive., Fletcher, Horace M., Forrester, Terrence E.. Ultrasound Derived Fetal Growth Curves for a Jamaican Population
• Smikle, Monica , Wharfe, Gillian H., Fletcher, Horace M., Reid, Marvin E., Roye-Green, Karen J., Frederick, Joseph, Pierangeli, Silvia S.. Anticardiolipin, other antiphospholipid antibody tests and diagnosis of the antiphospholipid syndrome
• Wharfe, Gillian H. , Fletcher, Horace M., Smikle, Monica , Frederick, Joseph , Reid, Marvin E.. The prevalence of positive anticardiolipin antibody in Jamaican women with spontaneous abortion and the correlation with past clinical history
• Gossell-Williams, Maxine D., Fletcher, Horace M., McFarlane-Anderson, Norma, Jacob, A., Patel, J., Zeisel, S.. Free Plasma Choline Concentrations During the First to Second Trimester of Pregnancy in Jamaican Women: Implications of Inaduquate Dietary Intake
• DaCosta, H., Fletcher, Horace M., Kulkarni, Santosh K., Phillip, H.. Correlation between transvaginal measured endometrical thickness and histopathological findings in black women with postmenopausal bleeding [abstract]
• Thame, Minerva M., Osmond, C., Fletcher, Horace M.., Forrester, Terrence E.. Ultrasound derived foetal growth curves for a Jamaican population [Abstract only]
• Scarlett, Marinna D.. , Isaacs, M. A. , Fredrick-Johnston, S. , Kulkarni, S. , McCaw-Binns, Affette M. , Fletcher, H. . Maternal mortality in patients admitted to an intensive care unit in Jamaica
• Fletcher, Horace M., Mullings, Anthony M., Forrester, Terrence E.. An open trial comparing isradipine with hydralazine and methyl dopa in patients with severe pre-eclampsia
• Walker, Susan P., Ewan-Whyte,C, Chang, Susan M., Powell, Christine A., Fletcher, Horace M., Grantham-McGregor, Sally M.. Factors associated with size at birth in Jamaican infants born at term [Abstract only]
• Rockhead, C., Fletcher, Horace, Morgan, Owen. Induction of labour with vaginal misoprostol: A comparison of 50ug twice daily (50bd) with 100ug used once daily (100od).
• Fletcher, Horace M, Wharfe, Gilian H., Mitchell, Sharmaine Y.. Placental separation due to lap seat belt injury during air travel.
• Bazuaye, P. E., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma. Class 1 HLA-A-B Haplotypes and Tumour Factors (TNF-ŕ) - 308 Polymorphism and Cervical Dysplasia [Abstract]
• Perry, D., Reid, Marvin E., Thame, Minerva M., Fletcher, Horace M., Mullings, Anthony M., McCaw-Binns, Affette M., King, D., Rattray, Carole A.. HIV infection seroprevalence and risk factor study among pregnant women attending the Antenatal Clinic at the University Hospital of the West Indies, Kingston, Jamaica
• Brooks, A., Wharfe, Gilian, Pedican, M., Fletcher, Horace, Williams, Nadia. Fatal pulmonary embolism in Jamaican women: A five year review of post mortems at UHWI
• Fletcher, Horace M., Mitchell, Sharmaine Y., Bennett, Franklyn I., Simms-Stewart, Donnette A., Scott, Paul W., Reid, Marvin E., Williams, Nadia P., Wharfe, Gilian H., Wilks, Rainford J.. Difference in cardiovascular disease risk profile and osteoporosis in Jamaican black women with surgical and natural menopause.
• Fletcher, Horace M., Hutchinson, S.E.. A retrospective review of pregnancy outcome after misoprostol (prostaglandin E1) induction of labour
• Phillip, H., DaCosta, Vernon E., Fletcher, Horace M., Kulkarni, Santosh K., Reid, Marvin E.. Correlation between transvaginal ultrasound measured endometrial thickness and histopathological findings in Afro-Caribbean Jamaican women with postmenopausal bleeding
• Fletcher, Horace M., Rattray, Carole A., Hanchard, Barrie, Vaughan, Kenneth D., West, Wayne M.. Disseminated donovanosis (Granuloma inguinale) with osteomyelitis of both wrists
• Fletcher, Horace M., Hanchard, Barrie. Poverty eradication and decreased human papilloma virus cancer of the penis and vulva in Jamaica
• Samuels, L.A., Christie, Loxley, Roberts-Gittens, B., Fletcher, Horace, Frederick, Joseph. The effect of hyoscine butylbromide on the first stage of labour in term pregnancies.
• Bazuaye, K.P., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma . Cervical dysplasia in Jamaican women: The role of lifestyle and sexual practices [abstract]
• Hardie, Joseph. M., Reid, Marvin E., Fletcher, Horace M., Wynter, Shaun H., Frederick, C.. Operative morbidity and reproductive outcome in secondary myomectomy: A prospective cohort study
• Wharfe, Gillian H. , Fletcher, Horace M., Mitchell, Sharmaine Y.. Placental Separation from a Seatbelt Injury Due to Severe Turbulence During Aeroplane Travel
• Simms-Stewart, D., DaCosta, Vernon E., Fletcher, Horace M., Reid, Marvin E.. Comparison Between Actual Birthweight, Ultrasonographic Fetal Weight and the Effect of the Level of Experience on the Accuracy of the Measurement
• Potter, T., Fletcher, Horace M., Vutchkov, Mitko K., Lalor, Gerald. C.. The Mercury Concentration in the Placentae of Parturients at the University Hospital of the West Indies and its Correlation to Known Risk Factors During Pregnancy [Abstract]
• Yam, Eileen A., Gordon-Strachan, Georgiana, McIntyre, Garth , Fletcher, Horace, Garcia, Sandra G., Becker, Davida, Ezcurra, Enrique . Jamaican and Barbadian health care providers’ knowledge, attitudes and practices regarding emergency contraceptive pills.
• Levy, Natricha, McFarlane-Anderson, Norma, Bramwell, G., Wierenga, Andrea M., Fletcher, Horace M.. Pre-Eclampsia in Jamaican Women: Blood Pressure, Nitric Oxide Status, Polymorphisms in the Nitric Oxide Synthase Gene and their Relationship to Pregnancy Outcome. [Abstract]
• Bazuaye, P. E., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma. The Association Between Tumor Necrosis factor (TNFa) - 308 Polymorphism and Cervical Dysplasia in Jamaican Women [Abstract]
• Bazuaye, P.E., Fletcher, Horace M., Smikle, Monica , Jackson, Maria D., McFarlane-Anderson, Norma. Class 1 HLA-A-B Haplotypes and Tumour Necrosis Factor (TNF-a) - 308 Polymorphism and Cervical dysplasia [Abstract]
• Gossell-Williams, M. , Fletcher, H. , Zeisel, S. H. . Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report
• Simms-Stewart, D. , Frederick, S. , Fletcher, H. , Char, G. , Mitchell, S. . Postmenopausal uterine inversion treated by subtotal hysterectomy
• West, W. , Fletcher, H. , Hanchard, B. , Rattray, C. , Vaughan, K. . Bilateral psoas abscess in a case of granuloma inguinale
• Mitchell, Sharmaine Y., Fletcher, Horace M., Williams, Elaine E.. Ovarian hyperstimulation syndrome associated with Clomiphene citrate
• Fletcher, Horace M., Mitchell, Sharmaine Y., Thomas, E.. Midazolam versus diazepam as sedation during laparoscopy under local anaesthesia.
• Frederick, Joseph, Fletcher, Horace M., Simeon, Donald T., Mullings, Anthony M., Hardie, Milton. Intramyometrial vasopressin as a haemostatic agent during myomectomy.
• Fletcher, Horace M., Kulkarni, Santosh K, Brown, E.. Successful pregnancy outcome after hysteroscopic adhesiolysis in Asherman's syndrome.
• Fletcher, Horace M., Mitchell, Sharmaine Y., Frederick, Joseph, Simeon, Donald T., Brown, D.. Intravaginal misoprostol versus dinoprostone as cervical ripening and labor-inducing agents.
• Levy, N, Bramwell, G, Wierenga, A, Fletcher, H, McFarlane-Anderson, N. Booking blood pressures and plasma nitrite in Jamaican women with pre-eclampsia
• Fletcher, Horace M., Mullings, Anthony M.. A randomised trial of low dose aspirin for primiparae in pregnancy.
• Fletcher, Horace M., McCaw-Binns, Affette M.. Rupture of the uterus after misoprostol induction of labour
• Fletcher, Horace M.. Painless depo-provera injections using the pinch technique
• Mitchell, Sharmaine Y., Fletcher, Horace M., Williams, Nadia P., Coard, Kathleen C.. In situ squamous cell carcinoma of endometrium associated with long-term intrauterine device (Dalkon shield) usage
• Fletcher, Horace M., Wharfe, Gilian H., Mitchell, Sharmaine/ Y./Simon, T.. Treatment of intractable vaginal bleeding with formaldehyde soaked packs
• Fletcher, Horace, Wharfe, Gillian, Williams, Elaine, Hanchard, Barrie, Mitchell, Derek I.G.. Multiple metachronous malignancies, one patient with three primary malignancies: a case report
• Walker, Susan P., Ewan-Whyte, C, Chang, Susan M., Powell, Christine A., Fletcher, Horace M., McDonald, D, Grantham-McGregor, Sally M. . Factors associated with size and proportionality at birth in term Jamaican infants
• Fletcher, Horace M., Hanchard, Barrie, Wharfe, Gillian H. , Blake, Garfield O., Wolff, Cynthia, Reynolds, A., Waugh, Nadeen, Reid, Marvin E.. Multiple Primary Malignancies in Jamaica: An Epidemiological Review [Abstract]
• Sorhaindo, A., Becker, David, Fletcher, Horace M., Garcia, Sandra G.,, Mitchell, E.. Exploring Knowledge and Attitudes about Emergency Contraceptive Pills Among University Students in Jamaica. A Qualitative Approach
• Fletcher, Horace M.. The Impact of Deportees on the Epidemic of Violent Crimes in Jamaica and Other Countries in the Region [Abstract]
• Fletcher, Horace M., McFarlane, Michael E., Shirley, Suzanne E., Clarke, W. F., Lyon, K. . Massive ascites secondary to severe endometriosis
• Fletcher, Horace M., Mitchell, Sharmaine Y., Simeon, Donald T., Frederick, Joseph, Brown, D.. Intravaginal misoprostol as a cervical ripening agent.
• Fletcher, Horace M., Frederick, Joseph, Hardie, Milton, Simeon, Donald T.. A randomized comparison of vasopressin and tourniquet as haemostatic agents during myomectomy.
• Coard, Kathleen C., Fletcher, Horace M. . Leiomyosarcoma of the uterus with a florid intravascular component ('intravenous leiomyosarcomatosis')
• Thame, M. , Trotman, H. , Osmond, C. , Fletcher, H. , Antoine, M. . Body composition in pregnancies of adolescents and mature women and the relationship to birth anthropometry
• Johnson, N., Fletcher, Horace M., Reid, Marvin E.. Effect of Labour Induction with Misoprostol on Pregnancy Outcome in Gravidas with Pre-Eclampsia [Abstract]
• Potter, T., Fletcher, Horace M., Reid, Marvin E.. Vasopressin Versus Normal Saline as Haemostatic Aids to Dissection at Vaginal Hysterectomy [Abstract]
• Brown, D., Fletcher, Horace M., Myrie, M., Reid, Marvin E.. Caesarean myomectomy a safe procedure: Retrospective case controlled study
• McFarlane-Anderson, Norma, Bazuaye, P.E., Jackson, Maria D., Smikle, Monica, Fletcher, Horace M.. Cervical dysplasia and cancer and the use of hormonal contraceptives in Jamaican women.
• Phillip, H., DaCosta,Vernon E., Fletcher, Horace M., Kulkarni, Santosh K.. Correlation between transvaginal ultrasound measured endometrial thickness and histopathological findings in black women with postmenopausal bleeding [abstract]
• Williams, Winston, Mullings, Anthony M., Fletcher, Horace M., Nicholson, Alison M., Reid, Marvin E.. Pre-operative vaginal antisepsis and post-operative bacterial load: The possible correlation with vault sepsis [abstract]
• Potter, T., Fletcher, Horace M., Reid, Marvin E.. Vasopressin as a hemostatic and dissection aid at vaginal hysterectomy
• Johnson, Nadine A., Fletcher, Horace M., Reid, Marvin E.. Depo medroxyprogesterone acetate (DMPA) therapy for uterine myomata prior to surgery
• Rockhead, C., Fletcher, Horace M., Reid, Marvin E., Morgan, Owen St.C. . A comparison of two methods of labor induction with vaginal misoprostol
• Sorhaindo, A., Becker, David, Fletcher, Horace M., Garcia, Sandra G.. Emergency Contraception Among University Students in Kingston, Jamaica: A Survey of Knowledge, Attitudes, and Practices
• Fletcher, Horace M., Wharfe, Gillian H., Mitchell, Sharmaine Y., Simon,Theresa. Treatment of intractable vaginal bleeding with formaldehyde soaked packs
• Clark, S., Blum, J., Blanchard, K., Galvao, L., Fletcher, Horace M., Winikoff, B. . Misoprostol use in obstetrics and gynecology in Brazil, Jamaica, and the United States
• Fletcher, Horace, Wharfe, Gilian, Williams, Elaine, Hanchard, Barrie, Mitchell, Derek . Multiple metachronous malignancies, one patient with three primary malignancies: A case report
• Simms-Stewart, D., Fletcher, Horace M., Mitchell, Sharmaine Y., Walters, E., Reid, Marvin E., Bennett, Franklyn I.. Low Bone Mineral Density in an Afro-Caribbean Jamaican Population and the Associated Risk Factors [Abstract]
• Fletcher, Horace M., Wharfe, Gillian H., Thomas, E.. Successful pregnancies in patients with the antiphospholipid syndrome treated with low-dose aspirin.
• Fletcher, Horace M.. Misoprostol (prostaglandin E1) for induction of labour.
• Fletcher, Horace M., Frederick, Joseph. An update on the management of uterine fibroids
• Williams, Nadia P. , Williams, Elaine E. , Fletcher, Horace M. . Smooth Muscle Tumours of the Vulva in Jamaica
• Fletcher, Horace M. . HIV in Jamaica: Are We Being Alarmist?
• Bazuaye, K.P., Jackson, Maria D., Smikle, Monica ., Fletcher, Horace M., Rattray, Carole A., McFarlane-Anderson, Norma . Cervical dysplasia and use of hormonal contraceptives in Jamaican women [abstract]
• Wharfe, Gillian H., Fletcher, Horace M., Reid, Marvin E. . Lupus anticoagulant in Jamaican primiparae and the clinical significance in asymptomatic patients
• Gossell-Williams, Maxine D., Fletcher, Horace, McFarlane-Anderson, Norma, Jacob, A., Patel, J., Zeisel, S.H. Dietary intake of choline and plasma choline concentrations in pregnant women in Jamaica
• Thame, Minerva M., Trotman-Edwards, Helen L., Fletcher, Horace M., Antoine, Mathias. Body Composition Between Pregnancies of Adolescent Girls and Mature Women and the Impact on Fetal Growth and Birthweight [Abstract]
• Gossell-Williams, M. , Fletcher, H. , Zeisel, S. H. . Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report
• McFarlane-Anderson, N. , Bazuaye, P. E. , Jackson, M. D. , Smikle, M. , Fletcher, H. M. . Cervical dysplasia and cancer and the use of hormonal contraceptives in Jamaican women
• DaCosta, Vernon E., Wynter, Shaun H., Frederick, Joseph , Wynter, Hugh H., Fletcher, Horace M.. Cervical pregnancy: Case report and literature review
• Fletcher, Horace, Crandon, Ivor W., Webster, Dwight. Maternal hydrocephalus in pregnancy and delivery: A report of two cases
• Blair, O., Fletcher, Horace M., Kulkarni, Santosh K. A randomised controlled trial of outpatient versus inpatient cervical cerclage
• Watt, Angela. , Garwood, D. , Jackson, M. , Younger, Novie, Ragin, C. , Smikle, M. , Fletcher, H. , McFarlane-Anderson, N. . High-risk and multiple human papillomavirus (HPV) infections in cancer-free Jamaican women

Abstract

• Simon, Garfield A., McFarlane-Anderson, Norma D., Fletcher, Horace M., Golden, Kerith D., Wharfe, Gilian H., Ogegbo, O., Bligh, Annie , Branford-White, C.J.. Phytoestrogen levels in Selected Jamaican Food C
• Simms-Stewart, Donnette A., Ennis, A.., Bambury, Ian G., Williams, Nadia P., Fletcher, Horace M.. A review of gestational trophoblastic disease at the University Hospital of the West Indies during the years 2002-2005 and a comparison with the data for the years 1994-1998.
• Watt, Angela I., Ragin, C., Younger, Novie O., Garwood, D., Jackson, Maria D., Smikle, Monica P., Fletcher, Horace M., McFarlane-Anderson, Norma D.. Human papilloma-virus (HPV) infection in Jamaican women

Conference Proceedings

• Fletcher, H., Wharfe, G., Williams, N., Barton, E.N.. Renal impairment as a complication of uterine fibroids
• Buchanan, K/./Flectcher, H.. A comparison of the patient characteristics and outcome of treatment of patients who were treated medically with a single dose methotrexate versus surgically for ectopic pregnancies
• Simon, G.A., McFarlane-Anderson, N., Fletcher, H., Golden, K., Wharfe, G.. Descriptive characteristics affecting uterine fibroids risk in Jamaican women : Role of oestrogen availability determinants